Article No
GTX24460
Specifications
| Application | IHC, IP, PLA, WB |
| Article No | GTX24460 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | MCM3 antibody |
| Supplier | GeneTex |
| Entrez Gene ID | 4172 |
| Gene Symbol | MCM3 |
| Immunogen | A 38-amino acid synthetic peptide, which represented a portion of human Minichromosome Maintenance Deficient 3 encoded in part by exons 10 and 11 (LocusLink ID 4172). |
| Isotype | IgG |
| Notes | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:2000 - 1:10000. IHC-P: 1:1000 - 1:5000. IP: 2 - 5 µg/mg lysate. PLA: 1:2000 - 1:40000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 50µl |
| Source / Host | rabbit |
| Species Reactivity | frog, human |
| Storage | 4°C |
| UniProt Number | P25205 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
