Article No
GTX28320
Specifications
| Application | ELISA, IHC |
| Article No | GTX28320 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | IL1 beta antibody [11E5] |
| Supplier | GeneTex |
| Entrez Gene ID | 3553 |
| Gene Symbol | IL1B |
| Immunogen | Recombinant human IL-1, beta. |
| Isotype | IgG1 |
| Notes | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
| Product Type | Antibodies Primary |
| Purification | Protein A Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P01584 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
