Article No
GTX52569
Specifications
| Application | Inhibition, Neutralization, WB |
| Article No | GTX52569 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 10H10 |
| Clone Type | monoclonal |
| Concentration | 500 ug/ml |
| Conjugation | Unconjugated |
| Description | BMP6 antibody [10H10] |
| Supplier | GeneTex |
| Entrez Gene ID | 654 |
| Gene Symbol | BMP6 |
| Immunogen | Human recombinant BMP-6 |
| Isotype | IgG2 |
| Notes | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein G Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P22004, Q4VBA3 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
