Article No
GTX84599
Specifications
| Application | FC, ICC, IF, WB |
| Article No | GTX84599 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 2B6 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | DYNC1LI1 antibody [2B6] |
| Supplier | GeneTex |
| Entrez Gene ID | 51143 |
| Gene Symbol | DYNC1LI1 |
| Immunogen | Full length human recombinant protein of human DYNC1LI1 (NP_057225) produced in HEK293T cell. |
| Isotype | IgG1 |
| Notes | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores. |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:500. ICC/IF: 1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | Q9Y6G9 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
