Antibodies Primary

ADAM10 Polyclonal Antibody

NEW
ADAM10 Polyclonal Antibody

Article No

JM-3201-100

Application

WB

Species Reactivity

human

Size

100 µg

Source / Host

rabbit

Shipping Information

4°C

Product insert

Suggested protocols

Specifications

Application WB
Article No JM-3201-100
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Clone Type polyclonal
Concentration 0.5 mg/ml
Conjugation Unconjugated
Description ADAM10 Polyclonal Antibody
Supplier MBL International Corp.
Isotype IgG
Notes Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-α, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-α, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
Alias Names MADm, CDw156, CD156c, kuz, EC 3.4.24.81, HsT18717
Product Type Antibodies Primary
Shipping Information 4°C
Size 100 µg
Source / Host rabbit
Species Reactivity human
Storage -20°C
Technical Specifications Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-α, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-α, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
Product Page Updated 2020-06-10T09:56:05.519Z

Shipping info

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