Article No
JM-3767-100
Antibodies Primary
AIB1/ATR (Ataxia Telangiecasia and Rad3 Related) Polyclonal Antibody
AIB1/ATR (Ataxia Telangiecasia and Rad3 Related) Polyclonal Antibody
Product insert
Suggested protocols
Specifications
| Application | WB |
| Article No | JM-3767-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | AIB1/ATR (Ataxia Telangiecasia and Rad3 Related) Polyclonal Antibody |
| Supplier | MBL International Corp. |
| Isotype | IgG |
| Notes | ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1. |
| Alias Names | ATR, Ataxia telangiectasia and Rad3 related FRAP, FRP1, FRAP-related protein 1 SCKL, SCKL1, Seckel syndrome |
| Product Type | Antibodies Primary |
| Shipping Information | 4°C |
| Size | 100 µl |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Storage | -20°C |
| Technical Specifications | ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1. |
| Product Page Updated | 2021-01-11T15:22:00.814Z |
Shipping info
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