Antibodies Primary

AIB1/ATR (Ataxia Telangiecasia and Rad3 Related) Polyclonal Antibody

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AIB1/ATR (Ataxia Telangiecasia and Rad3 Related) Polyclonal Antibody

Article No

JM-3767-100

Application

WB

Species Reactivity

human
mouse

Size

100 µl

Source / Host

rabbit

Shipping Information

4°C

Product insert

Suggested protocols

Specifications

Application WB
Article No JM-3767-100
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Clone Type polyclonal
Conjugation Unconjugated
Description AIB1/ATR (Ataxia Telangiecasia and Rad3 Related) Polyclonal Antibody
Supplier MBL International Corp.
Isotype IgG
Notes ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1.
Alias Names ATR, Ataxia telangiectasia and Rad3 related FRAP, FRP1, FRAP-related protein 1 SCKL, SCKL1, Seckel syndrome
Product Type Antibodies Primary
Shipping Information 4°C
Size 100 µl
Source / Host rabbit
Species Reactivity human, mouse
Storage -20°C
Technical Specifications ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1.
Product Page Updated 2020-06-10T09:56:05.519Z

Shipping info

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