Antibodies Primary

APP Polyclonal Antibody

NEW
APP Polyclonal Antibody

Article No

JM-6001-100

Application

WB

Species Reactivity

human
mouse
rat

Size

100 µg

Source / Host

rabbit

Shipping Information

4°C

Product insert

Suggested protocols

Specifications

Application WB
Article No JM-6001-100
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Clone Type polyclonal
Concentration 0.5 mg/ml
Conjugation Unconjugated
Description APP Polyclonal Antibody
Supplier MBL International Corp.
Isotype IgG
Notes Accumulation of the amyloid-β peptide (Aβ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer’s disease. The β-amyloid protein precursor (APP) is cleaved by β-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-β peptide, which is deposited in the brains of all suffers of Alzheimer’s disease.
Alias Names amyloid-b-peptide, amyloid beta peptide, Amyloid beta A4 protein, Alzheimer disease amyloid protein, ABPP, APPI, Cerebral vascular amyloid peptide,
Product Type Antibodies Primary
Research Area Neuroscience
Shipping Information 4°C
Size 100 µg
Source / Host rabbit
Species Reactivity human, mouse, rat
Storage -20°C
Technical Specifications Accumulation of the amyloid-β peptide (Aβ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer’s disease. The β-amyloid protein precursor (APP) is cleaved by β-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-β peptide, which is deposited in the brains of all suffers of Alzheimer’s disease.
Product Page Updated 2020-06-10T09:56:05.519Z

Shipping info

The delivery time for this item is approximately 8-15 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.