Assay & Detection

1,5-Anhydroglucitol Uptake Assay Kit (Cell-Based)

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1,5-Anhydroglucitol Uptake Assay Kit (Cell-Based)

Article No

JM-K684-50

Size

50 assays

Shipping Information

gel pack

Specifications

Article No JM-K684-50
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Description 1,5-Anhydroglucitol Uptake Assay Kit (Cell-Based)
Supplier MBL International Corp.
Notes 1,5-Anhydroglucitol (1,5-AG) is the 1-deoxy form of D-glucose. Its level in blood plasma has been used in clinical research to investigate short-term glycemic control levels in diabetic patients. Cereals and animal source proteins constitute the main 1,5-AG source for humans. Most of 1,5-AG is absorbed by renal tubules, and its levels in human body are highly regulated and relatively consistent. Glucose can act as a competitive inhibitor of 1,5-AG in blood. Therefore, glucose levels are inversely proportional to 1,5-AG concentrations. The physiological function of 1,5-AG is not well understood. Recent studies showed 1,5-AG uptake could be associated with sodium-dependent glucose transporter. BioVision’s 1,5-Anhydroglucitol Uptake Assay Kit utilizes a proprietary fluorescent 1,5-AG analog, which can be taken up by cells. However, this 1,5-AG analog cannot be fully utilized in glycolytic processes and thus accumulates inside the cells. Fluorescence generated by this analog is proportional to the cellular 1,5-AG uptake. The assay can be used to monitor 1,5-AG uptake by using fluorescent microscopy and flow cytometry. Phloretin, a compound that can inhibit glucose transporter and 1,5-AG cell uptake, is included in the kit as a control. This non-radioactive assay kit is easy-to-use and allows qualitative and quantitative measurements of 1,5-AG uptake in cultured cells
Product Type Assay & Detection
Shipping Information gel pack
Size 50 assays
Storage -20°C
Product Page Updated 2021-01-11T15:22:00.814Z

Shipping info

The delivery time for this item is approximately 8-15 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.