Article No
LS-C188733-0.25
ITGAM / CD11b
CD11b antibody LS-C188733 is an unconjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IF, IHC and IP.
Antibodies Primary
Specifications
| NCBI Number | 3684 |
| Application | FC, IF, IHC, IP |
| Article No | LS-C188733-0.25 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 5C6 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | CD11b antibody LS-C188733 is an unconjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IF, IHC and IP. |
| Recommended Dilution | FC (1:100) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 3684 |
| Gene Symbol | ITGAM |
| Immunogen | Thioglycollate-elicited Peritoneal Macrophages (TPM). |
| Isotype | IgG2b |
| Notes | CD11b antibody LS-C188733 is an unconjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IF, IHC and IP. |
| Alias Names | ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain |
| Product Type | Antibodies Primary |
| Protocol | Flo (1:100), IF, IHC, IHC-Fr, IP |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 0.25 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | -20°C |
| Substrate / Buffer | PBS, 0.09% Sodium Azide |
| Technical Specifications | Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes. |
| Product Page Updated | 2024-04-12T06:35:05.844Z |
