Article No
LS-C389452-100
BCL2 / Bcl-2
Bcl-2 antibody LS-C389452 is an unconjugated mouse monoclonal antibody to Bcl-2 (BCL2) (aa41-54) from human. It is reactive with human, chimpanzee, dog and other species. Validated for Flow, IF, IHC, IP and WB.
Antibodies Primary
Specifications
| NCBI Number | 596 |
| Application | FC, IF, IHC, IP, WB |
| Article No | LS-C389452-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 100/D5 + 124 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Bcl-2 antibody LS-C389452 is an unconjugated mouse monoclonal antibody to Bcl-2 (BCL2) (aa41-54) from human. It is reactive with human, chimpanzee, dog and other species. Validated for Flow, IF, IHC, IP and WB. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (0.5 - 1 ug/ml), WB (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 596 |
| Gene Symbol | BCL2 |
| Immunogen | A synthetic peptide, aa 41-54 (G aa PAPGIFSSQPG) of the human protein. Percent identity by BLAST analysis: Human, Chimpanzee, Cat, Pig, Dog (100%); Gorilla, Orangutan, Bovine, Goat (91%); Galago (82%). |
| Isotype | IgG1 k |
| Notes | Bcl-2 antibody LS-C389452 is an unconjugated mouse monoclonal antibody to Bcl-2 (BCL2) (aa41-54) from human. It is reactive with human, chimpanzee, dog and other species. Validated for Flow, IF, IHC, IP and WB. |
| Alias Names | BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. B-cell lymphoma 2 is an oncogene that regulates apoptosis, having both inducing and inhibiting functions. In cancer cells, Bcl2 binds pro-apoptotic proteins, preventing programmed cell death from occurring. Overexpression is seen in many cancers including lung, breast, prostate and lymphomas. In most follicular lymphomas, neoplastic germinal centers express high levels of the protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, Bcl2 antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | dog/canine, human, mammals, pig/porcine |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human BCL2 / Bcl-2 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
