Article No
LS-C391119-100
VCAM1 / CD106
CD106 antibody LS-C391119 is an unconjugated mouse monoclonal antibody to human CD106 (VCAM1). Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 7412 |
| Application | FC, IF, IHC |
| Article No | LS-C391119-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 1.4C3 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | CD106 antibody LS-C391119 is an unconjugated mouse monoclonal antibody to human CD106 (VCAM1). Validated for Flow, IF and IHC. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (1 - 2 ug/ml), IHC-P (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 7412 |
| Gene Symbol | VCAM1 |
| Immunogen | Stimulated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM-1 antibody. |
| Isotype | IgG1 k |
| Notes | CD106 antibody LS-C391119 is an unconjugated mouse monoclonal antibody to human CD106 (VCAM1). Validated for Flow, IF and IHC. |
| Alias Names | VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM-1 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. Optimal dilution of the VCAM-1 antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human VCAM1 / CD106 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
