Article No
LS-C392552-7
PTH / Parathyroid Hormone
Parathyroid Hormone antibody LS-C392552 is an unconjugated mouse monoclonal antibody to human Parathyroid Hormone (PTH) (aa1-34). Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 5741 |
| Application | FC, IF, IHC |
| Article No | LS-C392552-7 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 3H9 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Parathyroid Hormone antibody LS-C392552 is an unconjugated mouse monoclonal antibody to human Parathyroid Hormone (PTH) (aa1-34). Validated for Flow, IF and IHC. |
| Recommended Dilution | IHC-P (1:1) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 5741 |
| Gene Symbol | PTH |
| Immunogen | Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH. |
| Isotype | IgG2b k |
| Notes | Parathyroid Hormone antibody LS-C392552 is an unconjugated mouse monoclonal antibody to human Parathyroid Hormone (PTH) (aa1-34). Validated for Flow, IF and IHC. |
| Alias Names | PTH, Parathyroid hormone, Parathyroid hormone 1, Parathyrin, Parathormone, PTH1 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Epitope of this mAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Optimal dilution of the Parathyroid Hormone antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 7 ml |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | PBS, 0.01% BSA, 0.05% sodium azide |
| Technical Specifications | Human PTH / Parathyroid Hormone |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
| Volume | 7 ml |
