Article No
MEX002-6
Application | WB, FC, ELISA |
Article No | MEX002-6 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | C047-1 |
Clone Type | monoclonal |
Concentration | C047-1 |
Conjugation | Biotin |
Description | Anti-CD63 (LAMP-3) mAb-Biotin |
Supplier | MBL |
Immunogen | Human prostate carcinoma cell line (PC3) derived exosomes (prepared by ultracentrifugation from cultured supernatant) |
Isotype | IgG2b k |
Notes | CD63 antigen, also known as LAMP-3, is a tetraspanin characterized by four transmembrane domains and a member of the transmembrane 4 superfamily. CD63 is the first characterized tetraspanin. CD63 has broad tissue distribution and may play multiple roles in a variety of cellular processes such as immune response and tumorigenesis, but its function has not been elucidated entirely. It is reported that CD63 is abundant in tetraspanin-enriched microdomains (TEMs) and a certain type of cellular compartment, such as late endosomes and lysosomes, while the tetraspanin-rich small lipid bilayers are secreted into extracellular fluid as a certain type of extracellular vesicles, called exosome. Because of various exosome features, CD63, one of the representative exosome surface proteins, is thought to be related to intercellular communication. |
Product Type | Antibodies Primary |
Research area | Epigenetics |
Shipping Information | 4°C |
Size | 50 µl |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Technical Specifications | CD63 antigen, also known as LAMP-3, is a tetraspanin characterized by four transmembrane domains and a member of the transmembrane 4 superfamily. CD63 is the first characterized tetraspanin. CD63 has broad tissue distribution and may play multiple roles in a variety of cellular processes such as immune response and tumorigenesis, but its function has not been elucidated entirely. It is reported that CD63 is abundant in tetraspanin-enriched microdomains (TEMs) and a certain type of cellular compartment, such as late endosomes and lysosomes, while the tetraspanin-rich small lipid bilayers are secreted into extracellular fluid as a certain type of extracellular vesicles, called exosome. Because of various exosome features, CD63, one of the representative exosome surface proteins, is thought to be related to intercellular communication. |
Product Page Updated | 2023-12-29T16:20:16.638Z |