Article No
MONX11135
Mouse anti-HMB45 antigen , clone HMB45
Mouse anti-HMB45 antigen , clone HMB45
Antibodies Primary
Specifications
| Additional Information | The HMB45 antigen has also been identified in retinal pigment epithelium (RPE) but is reported to be reactive only with the transient prenatal and infantile RPE. No reaction is reported to be observed with intradermal nevi and normal adult melanocytes and non-melanocytic cells. Tumor cells of epithelial, lymphoid, glial and mesenchymal origin are reported to be negative. This clone is well described in the literature. It is indicated to label an intracytoplasmic antigen in the majority of melanomas and other tumors demonstrating melanoma/melanocytic differentiation. The clone is also reported to react with junctional and blue nevus cells. (Bacchi CE et al., A Review. Applied Immunohistochemistry. 4:73-85 (1996)). |
| Application | IHC |
| Article No | MONX11135 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | HMB45 |
| Clone Type | monoclonal |
| Concentration | Greater than or equal to 10.8 mg/L |
| Conjugation | Unconjugated |
| Description | Mouse anti-HMB45 antigen , clone HMB45 |
| Supplier | SANBIO bv/Monosan |
| Format | - |
| Immunogen | Extract of pigmented melanoma metastases from lymph nodes. |
| Isotype | IgG1 k |
| Notes | The HMB45 antigen has also been identified in retinal pigment epithelium (RPE) but is reported to be reactive only with the transient prenatal and infantile RPE. No reaction is reported to be observed with intradermal nevi and normal adult melanocytes and non-melanocytic cells. Tumor cells of epithelial, lymphoid, glial and mesenchymal origin are reported to be negative. This clone is well described in the literature. It is indicated to label an intracytoplasmic antigen in the majority of melanomas and other tumors demonstrating melanoma/melanocytic differentiation. The clone is also reported to react with junctional and blue nevus cells. (Bacchi CE et al., A Review. Applied Immunohistochemistry. 4:73-85 (1996)). |
| Product Type | Antibodies Primary |
| Protocol | IHC-P (1:60) |
| Shipping Information | blue ice |
| Size | 1 ml |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 2-8°C |
| Substrate / Buffer | Tissue culture supernatant with Sodium azide |
| Product Page Updated | 2024-01-12T18:37:31.725Z |
