Article No
N01269H-1
Specifications
| Application | IA, Preservation, WB |
| Article No | N01269H-1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | monoclonal |
| Concentration | 5.0 mg/mL (OD280nm) |
| Conjugation | Unconjugated |
| Description | Mab to D-Dimer |
| Supplier | Meridian Life Science |
| Format | Purified |
| Keywords | MAb to Cardiac Markers |
| Notes | This antibody is highly specific for D-dimer. The epitope recognized by 3B6 resides between amino acids 86 and 302 in the gamma chain of the D domain chains of fibrinogen (i.e., Fragment D). This epitope is masked in soluble non-cross linked or non-degraded fibrin but after cross-linked fibrin has been cleaved by plasmin, it becomes expressed. Expression of this region, which is specific to fibrin derivatives, can be utilized to differentiate between fibrin and fibrinogen breakdown products. The smallest and best characterized of the fibrin breakdown products is D-dimer, comprising two cross-linked D domains.This clone demonstrates reactivity with D-dimer and other cross-linked fibrin degradation products containing D-dimer, but no reactivity with Fragment D or E. Additionally, no cross-reaction was found with purified intact fibrinogen or fibrinogen degradation products. |
| Product Type | Antibodies Primary |
| Protocol | Suitable for use in ELISA, Western Blot and Lateral Flow. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.Recommended antibody pairs for sandwich immunoassay:Capture N01270M Detection N01269H |
| Purity | ≥ 90% pure (HPLC 280 nm). ProSepA Chromatography |
| Research area | Immunology |
| Shipping Information | Dry Ice |
| Size | 1 MG |
| Source / Host | mouse |
| Storage | Store at ≤ 65°C. |
| Substrate / Buffer | No Preservative |
| Product Page Updated | 2024-01-15T11:23:28.230Z |
