Article No
P010-1MG
Specifications
| CAS No | 58880-19-6 |
| Article No | P010-1MG |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Components | Inhibitor / activator |
| Description | Trichostatin A |
| Supplier | Arbor Assays |
| Notes | Trichostatin A is a potent, reversible inhibitor of histone deacetylase (HDAC) with a Ki of 3.4 nM. In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of the HDAC1 with an IC50 value of 70 nM. Trichostatin A selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. Induces accelerated dedifferentiation of primordial germ cells into embryonic germ cells. Potent anti-cancer agent. |
| Product Type | Chemicals & Biochemicals |
| Research area | Molecular Biology |
| Shipping Information | BLUE ICE |
| Size | 1MG |
| Species Reactivity | synthetic |
| Storage | RT |
| Product Page Updated | 2024-03-04T10:32:24.675Z |
