Antibodies Primary

ROR2

NEW
Anti-ROR2 (Human) mAb

Article No

W361-3

Application

FC

Species Reactivity

human

Size

100 µl

Clone

7C9D6

Source / Host

mouse

Shipping Information

4°C

Product insert

Specifications

Application FC
Article No W361-3
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Clone 7C9D6
Clone Type monoclonal
Description Anti-ROR2 (Human) mAb
Supplier MBL International Corp.
Immunogen Human ROR2 expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Isotype IgG2a k
Notes Receptor tyrosine kinase-like orphan receptor 2, also known as ROR2, belongs to a family of the receptor tyrosine kinases. While ROR2 is highly expressed during early embryonic development, it has low expression levels in adult tissues. ROR2 has been known to play key roles in developmental morphogenesis, particularly in the formation of cartilage-derived skeleton. Disruption of mouse Ror2 leads to profound skeletal abnormalities. In humans, mutations in <em>ROR2</em> are found in brachydactyly type B1, characterized by hypoplasia of the distal and middle phalanges. ROR2 deficiency is also associated with recessive Robinow syndrome, resulting in shortening of limbs, facial dysmorphia, and spinal defects.
Alias Names signal sequence trap, SST-REX, stem cell, mesenchymal stem cell, MSC, 7C9D6, BDB, BDB1, Receptor tyrosine kinase-like orphan receptor 2, NTRKR2
Product Type Antibodies Primary
References 1) Liu, Y., et al., Mol. Endocrinol. 21, 3050-3061 (2007) 2) van Bolhoven, H., et al., Nat. Genet. 25, 423-426 (2000) 3) Afzal, A. R., et al., Nat. Genet. 25, 419-422 (2000) 4) Kojima, T. and Kitamura,T., Nat. Biotechnol. 17, 487-490 (1999)
Shipping Information 4°C
Size 100 µl
Source / Host mouse
Species Reactivity human
Storage -20°C
Substrate / Buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Product Page Updated 2020-06-10T09:56:05.519Z

Shipping info

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