5-HTR2

Article No bs-1056R
Product Type Antibodies Primary
Research Area Neuroscience
Application WB, IHC, IF
Size 100ul

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Specifications

Country Availability DK, EE, FI, FO, GL, IS, LT, LV, NO, SE
Clone Type polyclonal
Concentration 1ug/ul
Conjugation Unconjugated
Data Sheet Link https://www.biossusa.com/store/datasheets/bs-1056R
Description 5-HTR2 Polyclonal Antibody
Supplier Bioss Inc
Entrez Gene ID 3356
Isotype IgG
Notes G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
Alias Names HTR2; 5-HT2A; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A; HTR2A
Protocol WB(1:300-1000), IHC-P(1:200-400), IF(IHC-P)(1:50-200)
Purification Purified by Protein A.
Source / Host rabbit
Species Reactivity human, mouse, rat
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Technical Specifications KLH conjugated synthetic peptide derived from human 5-HTR2A
Product Page Updated 2019-01-03T14:43:56.134Z

Shipping info

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Source/Host:

rabbit rabbit

Species reactivity:

human, mouse, rat human mouse rat

Product insert:

Product data sheet

Datasheet